Nerve Growth Factor Interactions with Mast Cells

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Mast Cell-Nerve Interactions.

Mutual associations between nerves and mast cells have been observed in normal conditions and in pathological ones such as human irritable bowel syndrome, atopic dermatitis, interstitial cystitis, and more. Here we review the recent literature in this field, putting emphasis on the enteric, skin, and urinary systems, and the pathophysiological implications of this interaction in them.

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Induction of Bone Marrow Stromal Cells into Cholinergic-Like Cells by Nerve Growth Factor

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Nerve growth factor prevents apoptosis of rat peritoneal mast cells through the trk proto-oncogene receptor.

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Co-expression of recombinant human nerve growth factor with trigger factor chaperone in E. coli

Nerve growth factor (NGF) is a neurotrophic factor that is functional in the survival, maintenance and differentiation of nervous system cells. This protein has three subunits, of which the beta subunit has the main activity. Its structure consists of a cysteine knot motif made up of beta strands linked by disulfide bonds. It can be used as a therapeutic agent in the treatment of many diseases....

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ژورنال

عنوان ژورنال: International Journal of Immunopathology and Pharmacology

سال: 2014

ISSN: 2058-7384,2058-7384

DOI: 10.1177/039463201402700103